eagle-i Jackson State UniversityJackson State University
See it in Search
This page is a preview of the following resource. Continue onto eagle-i search using the button on the right to see the full record.

Pericardial Fat and Echocardiographic Measures of Cardiac Abnormalities: The Jackson Heart Study.

eagle-i ID

http://jsu.eagle-i.net/i/0000012e-0b27-1110-d3a1-177580000000

Resource Type

  1. Cohort study

Properties

  1. Additional Topic(s)
    Echocardiography
  2. Additional Topic(s)
    Obesity
  3. Resource Description
    Abstract OBJECTIVE- Pericardial adipose tissue (PAT), a regional fat depot adjacent to the myocardium, may mediate the complex relation between obesity and cardiac left ventricular (LV) abnormalities. We sought to evaluate the association of PAT with echocardiographic measures of LV abnormalities in the Jackson Heart Study (JHS). RESEARCH DESIGN AND METHODS A total of 1,414 African Americans (35% men; mean age 58 years) from the JHS underwent computed tomographic assessment of PAT and abdominal visceral adipose tissue (VAT) from 2007 to 2009 and echocardiography examination between 2000 and 2004. Echocardiographic measures of left atrial (LA) internal diameter, LV mass, LV ejection fraction (LVEF), and E-wave velocity-to-A-wave velocity ratio (E/A ratio) were examined in relation to PAT, VAT, BMI, and waist circumference (WC). RESULTS All adiposity measures were positively correlated with LA diameter and LV mass and negatively correlated with E/A ratio (P = 0.02 to 0.0001) and were not with LVEF (P = 0.36-0.61). In women, per 1-SD increment of PAT, we observed association with higher LV mass (9.0 ± 1.7 gm, P = 0.0001) and LA diameter (1.0 ± 0.1 mm, P = 0.0001). However, the magnitude of the association between PAT and cardiac measures was similar compared with VAT (P = 0.65 [LV mass]; P = 0.26 [LA diameter]) and was smallercompared with BMI (P = 0.002 [LV mass]; P = 0.01 [LA diameter]) and WC (P = 0.009 [LA diameter]). CONCLUSIONS PAT is correlated with echocardiographic measures of cardiac LV abnormalities, but the association is not stronger than other adiposity measures.
  4. Contact
    Taylor, Jr., Herman A.
  5. PI
    Taylor, Jr., Herman A.
  6. Topic
    heart disease
  7. Study Population
    1,414 African Americans (35% men; mean age 58 years)
  8. Related Publication or Documentation
    Pericardial fat and echocardiographic measures of cardiac abnormalities: the Jackson Heart Study.
  9. Funded by
    National Center for Minority Health and Health Disparities
  10. Funded by
    National Heart, Lung, and Blood Institute
  11. Performed by
    Jackson Heart Study
 
RDFRDF
 
Provenance Metadata About This Resource Record
  1. workflow state
    Published
  2. contributor
    nvasilevsky
  3. created
    2011-02-09T10:03:32.171-06:00
  4. creator
    sgarner (Solomon Garner)
  5. modified
    2011-05-18T12:41:44.292-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016