eagle-i Jackson State UniversityJackson State University

Laboratories at Jackson State University

This is a summary list of all laboratories at Jackson State University . The list includes links to more detailed information, which may also be found using the eagle-i search app.

Ashton Hamme Laboratory


Our research focuses on the synthesis of natural occurring compounds that have anti-cancer properties, specifically breast cancer. We also synthesize compounds that are similar to natural products, which are called synthetic analogues, and submit them for biological testing. After we receive the biological profile of the synthetic analogues, we modify the functional groups in hopes of increasing the biological activity of the synthetic analogues. We use the structure activity relationship (SAR) to determine which functional groups are necessary for the biological activity of a particular compound series, and the tolerance of the binding pocket towards molecular size and electronics. Thus far, our molecular targets are isoxazolines and spiroisoxazolines that are similar to the ones found in the naturally occurring compound, 11-deoxyfistularin-3, which is cytotoxic against mcf-7 breast cancer tissue. The isoxazolines and spiroisoxazolines are synthesized through a 1,3-dipolar cycloaddition of functionalized alkenes. A student in our research group will learn about the art of organic synthesis, and the techniques that are used to isolate, purify, and identify organic compounds. These skills will be valuable for a student who is interested in a career in organic synthesis and medicinal chemistry.

Bioanalytical Chemistry Laboratory


Our research is focused on method development for the quantification of chemical species of biomedical interest. The research involves the use of a wide range of modern analytical instruments including HPLC-MS/MS, laser induced fluorescence spectrometry, and GC-MS.

Carolyn Howard Lab


Our research focuses on
* Risk factors in breast cancer development
* Cytochrome P450 modulation in response to drug treatment
* Health disparities in cancer
* Validation of Vernonia amygdalina as a chemotherapeutic agent
* Natural products as anti-cancer treatment alternatives
* Causal factors in disparities in professional advancement and in health among women

Ken Lee Laboratory


This laboratory is involved in organic chemistry research, in particular: 1/Organic Synthesis (Structure modification of Aromatase Inhibitors for introducing carboxylic group to ligate transition metals, Development of Agmatinase Inhibitors), 2: Renewable Energy (Separation and Hydrolysis of Cellulose from Sawdust, Formation of Biodiesel), 3: Speciation of Cytotoxic Chemical Components from the plant, Vernonia amygdalina

Found 4   laboratories .

This institution proudly participates in the eagle-i Network. Use the search bar above to search more than 90,000 biomedical research resources currently listed in eagle-i from more than 28 institutions. Not sure what you're looking for? Choose "Browse" at the top of the page to see organisms, instruments, reagents, services and more.

To learn more about the eagle-i Network, resources and institutions, please visit www.eagle-i.net.
Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016